Nicholas Murgolo: search on Z-Library

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1

PepPat, a pattern-based oligopeptide homology search method and the identification of a novel tachykinin-like peptide

Ying Jiang, Ge Gao, Gang Fang, Eric L. Gustafson, Maureen Laverty, Yanbin Yin, Yong Zhang, Jingchu Luo, Jonathan R. Greene, Marvin L. Bayne, Joseph A. Hedrick, Nicholas J. Murgolo

Journal:

Mammalian Genome

Year:

2003

Language:

english

File:

PDF, 261 KB

english, 2003

2

Type I interferon structures: Possible scaffolds for the interferon-alpha receptor complex

Nagabhushan, Tattanahalli L, Reichert, Paul, Walter, Mark R, Murgolo, Nicholas J

Journal:

Canadian Journal of Chemistry

Year:

2002

File:

PDF, 605 KB

2002

3

X-Ray Structure of Trypanothione Reductase from Crithidia fasciculata at 2.4-Å Resolution

John Kuriyan, Xiang-Peng Kong, T. S. R. Krishna, Robert M. Sweet, Nicholas J. Murgolo, Helen Field, Anthony Cerami and Graeme B. Henderson

Journal:

Proceedings of the National Academy of Sciences

Year:

1991

Language:

english

File:

PDF, 1.50 MB

english, 1991

4

Discovery of Novel Chemotypes to a G-Protein-Coupled Receptor through Ligand-Steered Homology Modeling and Structure-Based Virtual Screening

Cavasotto, Claudio N., Orry, Andrew J. W., Murgolo, Nicholas J., Czarniecki, Michael F., Kocsi, Sue Ann, Hawes, Brian E., O’Neill, Kim A., Hine, Heather, Burton, Marybeth S., Voigt, Johannes H., Abagy

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 904 KB

english, 2008

5

Murgocil is a Highly Bioactive Staphylococcal-Specific Inhibitor of the Peptidoglycan Glycosyltransferase Enzyme MurG

Mann, Paul A., Müller, Anna, Xiao, Li, Pereira, Pedro M., Yang, Christine, Ho Lee, Sang, Wang, Hao, Trzeciak, Joanna, Schneeweis, Jonathan, dos Santos, Margarida Moreira, Murgolo, Nicholas, She, Xinwe

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 2.28 MB

english, 2013

6

Presenilin mutations in Alzheimer's disease: molecular models suggest a potential functional locus

Nicholas J. Murgolo, Joan E. Brown, Marvin L. Bayne, Catherine D. Strader

Journal:

Trends in Pharmacological Sciences

Year:

1996

Language:

english

File:

PDF, 1.28 MB

english, 1996

7

Chemical Genomics-Based Antifungal Drug Discovery: Targeting Glycosylphosphatidylinositol (GPI) Precursor Biosynthesis

Mann, Paul A., McLellan, Catherine A., Koseoglu, Sandra, Si, Qian, Kuzmin, Elena, Flattery, Amy, Harris, Guy, Sher, Xinwei, Murgolo, Nicholas, Wang, Hao, Devito, Kristine, de Pedro, Nuria, Genilloud,

Journal:

ACS Infectious Diseases

Year:

2015

Language:

english

File:

PDF, 2.58 MB

english, 2015

8

Engineering the Substrate Specificity of Glutathione Reductase Toward that of Trypanothione Reduction

Graeme B. Henderson, Nicholas J. Murgolo, John Kuriyan, Klara Osapay, Dorothea Kominos, Alan Berry, Nigel S. Scrutton, Nigel W. Hinchliffe, Richard N. Perham and Anthony Cerami

Journal:

Proceedings of the National Academy of Sciences

Year:

1991

Language:

english

File:

PDF, 894 KB

english, 1991

9

Mutation Detection in an Antibody-Producing Chinese Hamster Ovary Cell Line by Targeted RNA Sequencing

Zhang, Siyan, Hughes, Jason D., Murgolo, Nicholas, Levitan, Diane, Chen, Janice, Liu, Zhong, Shi, Shuangping

Journal:

BioMed Research International

Year:

2016

Language:

english

File:

PDF, 2.53 MB

english, 2016

10

Antibacterial small molecules targeting the conserved TOPRIM domain of DNA gyrase

Walker, Scott S., Labroli, Marc, Painter, Ronald E., Wiltsie, Judyann, Sherborne, Brad, Murgolo, Nicholas, Sher, Xinwei, Mann, Paul, Zuck, Paul, Garlisi, Charles G., Su, Jing, Kargman, Stacia, Xiao, L

Journal:

Year:

2017

Language:

english

File:

PDF, 15.98 MB

english, 2017

11

Proprotein convertase subtilisin/kexin type 9 (PCSK9) affects gene expression pathways beyond cholesterol metabolism in liver cells

Hong Lan, Ling Pang, Marsha M. Smith, Diane Levitan, Wei Ding, Li Liu, Lixin Shan, Vidhi V. Shah, Maureen Laverty, Gladys Arreaza, Qing Zhang, Nicholas J. Murgolo, Marco Hernandez, Jonathan R. Greene,

Journal:

Journal of Cellular Physiology

Year:

2010

Language:

english

File:

PDF, 328 KB

english, 2010

12

Discovery of Wall Teichoic Acid Inhibitors as Potential Anti-MRSA β-Lactam Combination Agents

Wang, Hao, Gill, Charles J., Lee, Sang H., Mann, Paul, Zuck, Paul, Meredith, Timothy C., Murgolo, Nicholas, She, Xinwei, Kales, Susan, Liang, Lianzhu, Liu, Jenny, Wu, Jin, Santa Maria, John, Su, Jing,

Journal:

Chemistry & Biology

Year:

2013

Language:

english

File:

PDF, 1.44 MB

english, 2013

13

Functional defects in Clostridium difficile TcdB toxin uptake identify CSPG4 receptor binding determinants

Gupta, Pulkit, Zhang, Zhifen, Sugiman-Marangos, Seiji N, Tam, John, Raman, Swetha, Julien, Jean-Philippe, Kroh, Heather K., Lacy, D. Borden, Murgolo, Nicholas, Bekkari, Kavitha, Therien, Alex G, Herna

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 2.31 MB

english, 2017

14

The Three-Dimensional Solution Structure of the Src Homology Domain-2 of the Growth Factor Receptor-Bound Protein-2

Mary M. Senior, Anne F. Frederick, Stuart Black, Nicholas J. Murgolo, Louise M. Perkins, Oswald Wilson, Mark E. Snow, Yu-Sen Wang

Journal:

Journal of Biomolecular NMR

Year:

1998

Language:

english

File:

PDF, 169 KB

english, 1998

15

KCa3.1: target and marker for cancer, autoimmune disorder and vascular inflammation?

Chou, Chuan-Chu, Lunn, Charles A, Murgolo, Nicholas J

Journal:

Expert Review of Molecular Diagnostics

Year:

2008

Language:

english

File:

PDF, 355 KB

english, 2008

16

Selective small-molecule inhibition of an RNA structural element

Howe, John A., Wang, Hao, Fischmann, Thierry O., Balibar, Carl J., Xiao, Li, Galgoci, Andrew M., Malinverni, Juliana C., Mayhood, Todd, Villafania, Artjohn, Nahvi, Ali, Murgolo, Nicholas, Barbieri, Ch

Journal:

Year:

2015

Language:

english

File:

PDF, 3.35 MB

english, 2015

17

Improving Antibody Production In Stably Transfected CHO Cells by CRISPRâCas9âmediated Inactivation of Genes Identified in a Large Scale Screen with Chinese Hamsterâspecific siRNAs

Lin, PaoâChun, Liu, Ren, Alvin, Krista, Shahreel, Wahyu, Murgolo, Nicholas, Ye, Jianxin, Du, Zhimei, Song, Zhiwei

Journal:

Biotechnology Journal

Year:

2020

File:

PDF, 1.97 MB

2020

18

Regulation of two rat mas-related genes in a model of neuropathic pain

Eric L. Gustafson, Maureen Maguire, Marilena Campanella, Glauco Tarozzo, Yuping Jia, Xiao-Wei Dong, Maureen Laverty, Nicholas Murgolo, Tony Priestley, Angelo Reggiani, Frederick Monsma, Massimo Beltra

Journal:

Molecular Brain Research

Year:

2005

Language:

english

File:

PDF, 441 KB

english, 2005

19

Crystallization and preliminary X-ray investigation of recombinant human interleukin 10

William J. Cook, William T. Windsor, Nicholas J. Murgolo, Stephen H. Tindall, Tattanahalli L. Nagabhushan, Mark R. Walter

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1995

Language:

english

File:

PDF, 435 KB

english, 1995

20

Discovery of N -Alkyl-5-hydroxypyrimidinone Carboxamides as Novel Antitubercular Agents Targeting Decaprenylphosphoryl-β-D-ribose 2′-oxidase (DprE1) and Their Structure-activity Relationship Study

Oh, Sangmi, Park, Yumi, Engelhart, Curtis A., Wallach, Joshua B., Schnappinger, Dirk, Arora, Kriti, Manikkam, Michelle, Gac, Brian, Wang, Hongwu, Murgolo, Nicholas, Olsen, David B, Goodwin, Michael, S

Journal:

Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 559 KB

english, 2018

21

Two related neurokinin-1 receptor antagonists have overlapping but different binding sites

Scott Greenfeder, Boonlert Cheewatrakoolpong, John Anthes, Motasim Billah, Robert W Egan, Joan E Brown, Nicholas J Murgolo

Journal:

Bioorganic & Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 105 KB

english, 1998

22

A homology model of human interferon α-2

Dr. Nicholas J. Murgolo, William T. Windsor, Alan Hruza, Paul Reichert, Anthony Tsarbopoulos, Samuel Baldwin, Eric Huang, Birendra Pramanik, Steven Ealick, Paul P. Trotta

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1993

Language:

english

File:

PDF, 1.15 MB

english, 1993

23

PCSK9 binds to multiple receptors and can be functionally inhibited by an EGF-A peptide

LiXin Shan, Ling Pang, Rumin Zhang, Nicholas J. Murgolo, Hong Lan, Joseph A. Hedrick

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 370 KB

english, 2008

24

The N4 nitrogen of pirenzepine is responsible for selective binding of the M1 subtype human muscarinic receptor

Nicholas J. Murgolo, Joseph Kozlowski, Melissa A.B. Tice, Frank P. Hollinger, Joan E. Brown, Guowei Zhou, Lisa A. Taylor, Robert D. McQuade

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 234 KB

english, 1996

25

Preliminary crystallographic analysis of trypanothione reductase from Crithidia fasciculata

John Kuriyan, Lim Wong, Brian D. Guenther, Nicholas J. Murgolo, Anthony Cerami, Graeme B. Henderson

Journal:

Journal of Molecular Biology

Year:

1990

Language:

english

File:

PDF, 272 KB

english, 1990

26

Trypanothione Reductase

NICHOLAS J. MURGOLO, ANTHONY CERAMI, GRAEME B. HENDERSON

Journal:

Annals of the New York Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 456 KB

english, 1989

27

Affinity Selection–Mass Spectrometry Identifies a Novel Antibacterial RNA Polymerase Inhibitor

Walker, Scott S., Degen, David, Nickbarg, Elliott, Carr, Donna, Soriano, Aileen, Mandal, Mihir, Painter, Ronald E., Sheth, Payal, Xiao, Li, Sher, Xinwei, Murgolo, Nicholas, Su, Jing, Olsen, David B.,

Journal:

ACS Chemical Biology

Year:

2017

Language:

english

File:

PDF, 2.39 MB

english, 2017

28

Evaluation of CYP1A1 and CYP2B1/2 m-RNA Induction in Rat Liver Slices Using the NanoString® Technology: A Novel Tool for Drug Discovery Lead Optimization

Palamanda, Jairam, Kumari, Pramila, Murgolo, Nicholas, Benbow, Larry, Lin, Xinjie, Nomeir, Amin

Journal:

Drug Metabolism Letters

Year:

2009

Language:

english

File:

PDF, 119 KB

english, 2009

29

Structural and Biological Stability of the Human Interleukin 10 Homodimer†

Syto, Rosalinda, Murgolo, Nicholas J., Braswell, Emory H., Mui, Philip, Huang, Eric, Windsor, William T.

Journal:

Year:

1998

Language:

english

File:

PDF, 178 KB

english, 1998

30

The conformation of dolichol

Murgolo, Nicholas J., Patel, Akhileswar, Stivala, Salvatore S., Wong, Tommy K.

Journal:

Year:

1989

Language:

english

File:

PDF, 795 KB

english, 1989

31

Targeted deletion of Gpbar1 protects mice from cholesterol gallstone formation

Vassileva, Galya, Golovko, Andrei, Markowitz, Lisa, Abbondanzo, Susan J., Zeng, Ming, Yang, Shijun, Hoos, Lizbeth, Tetzloff, Glen, Levitan, Diane, Murgolo, Nicholas J., Keane, Kevin, Davis, Harry R.,

Journal:

Biochemical Journal

Year:

2006

Language:

english

File:

PDF, 707 KB

english, 2006

32

Broad Coverage of Genetically Diverse Strains of Clostridium difficile by Actoxumab and Bezlotoxumab Predicted by In Vitro Neutralization and Epitope Modeling

Hernandez, Lorraine D., Racine, Fred, Xiao, Li, DiNunzio, Edward, Hairston, Nichelle, Sheth, Payal R., Murgolo, Nicholas J., Therien, Alex G.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2015

Language:

english

File:

PDF, 2.05 MB

english, 2015

33

Structure and humanization of a rat monoclonal Fab to human interleukin-5

Cook, William J., Walter, Leigh J., Murgolo, Nicholas J., Chou, Chuan-Chu, Petro, Mary, Zavodny, Paul J., Narula, Satwant K., Ramanathan, Lata, Trotta, Paul P., Nagabhushan, Tattanahalli L.

Journal:

Protein Engineering Design and Selection

Year:

1996

Language:

english

File:

PDF, 5.60 MB

english, 1996

34

The neurokinin-1 and neurokinin-2 receptor binding sites of MDL103,392 differ

Scott Greenfeder, Boonlert Cheewatrakoolpong, Motasim Billah, Robert W Egan, Elizabeth Keene, Nicholas J Murgolo, John C Anthes

Journal:

Bioorganic & Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 394 KB

english, 1999

35

Clinical resistance to vicriviroc through adaptive V3 loop mutations in HIV-1 subtype D gp120 that alter interactions with the N-terminus and ECL2 of CCR5

Robert A. Ogert, Yan Hou, Lei Ba, Lisa Wojcik, Ping Qiu, Nicholas Murgolo, Jose Duca, Lisa M. Dunkle, Robert Ralston, John A. Howe

Journal:

Year:

2010

Language:

english

File:

PDF, 1.64 MB

english, 2010

36

Linking High-Throughput Screens to Identify MoAs and Novel Inhibitors of Mycobacterium tuberculosis Dihydrofolate Reductase

Santa Maria, John P., Park, Yumi, Yang, Lihu, Murgolo, Nicholas, Altman, Michael D, Zuck, Paul, Adam, Greg, Chamberlin, Chad, Saradjian, Peter, Dandliker, Peter, Boshoff, Helena I. M., Barry, Clifton

Journal:

ACS Chemical Biology

Year:

2017

Language:

english

File:

PDF, 1.16 MB

english, 2017

37

Chemical Genetic Analysis and Functional Characterization of Staphylococcal Wall Teichoic Acid 2-Epimerases Reveals Unconventional Antibiotic Drug Targets

Mann, Paul A., Müller, Anna, Wolff, Kerstin A., Fischmann, Thierry, Wang, Hao, Reed, Patricia, Hou, Yan, Li, Wenjin, Müller, Christa E., Xiao, Jianying, Murgolo, Nicholas, Sher, Xinwei, Mayhood, Todd,

Journal:

Year:

2016

Language:

english

File:

PDF, 4.70 MB

english, 2016

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